The Schierstein Bridge has connected the Wiesbaden district of Schierstein with the Mainz suburb of Mombach since 1962. The four-lane, 1282-metre-long A 643 freeway bridge was built in three years from six sections, including one hundred meters of prestressed concrete, and together with the Theodor Heuss Bridge and the Weisenau Bridge on the A 60 is one of the three road bridges connecting Hesse with Mainz.

There are combined cycle paths and footpaths on both sides of the lanes and a staircase leads up to the Rettbergsaue on the upstream side. As the bridge was originally designed for a federal highway, the Mombach junction only has very short deceleration and acceleration lanes.

Over the years, the structure has been severely affected by traffic volumes of around 80,000 vehicles per day, so that extensive renovation work had to be carried out between 1997 and 2000.

Since 2006, it has been clear that the bridge can no longer meet the requirements and that further renovation is impossible. As, according to an expert opinion, the structure can only be used until 2015, the maximum speed was limited to 60 km/h in 2007. Since 2008, vehicles coming from the direction of Mainz have been controlled by a stationary speed monitoring system on the Wiesbaden side.

Due to the dilapidated structure, the decision to build a new one was made in 2007. By 2018, a new, 1285-metre-long bridge with six lanes is to be built around 22 meters north of the current structure.