On March 30, 1945, the Americans commissioned Rudolf Jesinghaus-Medicus from Wiesbaden with the care of Holocaust survivors. The municipal care center for politically, racially and religiously persecuted people was under the authority of the welfare department head Philipp Holl and was housed in the welfare office at Lehrstraße 10.

Jesinghaus campaigned vehemently for the group of people entrusted to his care. His tasks included requisitioning living space, providing for former concentration camp prisoners passing through and locating concentration camp inmates who had not yet returned or finding out more about their fate. It was on his initiative that an appeal "To the concentration camp returnees and politically persecuted" was issued, with which Lord Mayor Georg Krücke welcomed the returnees and assured them of all possible help. He also initiated a "relief organization for those persecuted by the NSDAP", which was set up in July 1945 and called on the population to make donations.

However, the relationship between the municipal support office and the city administration, as well as with the military government, became increasingly difficult. Jesinghaus demanded more staff and better equipment for his office and complained about the increasing bureaucracy. Despite everything, the municipal support office continued to be an important point of contact.

In the second half of the year, the newly founded Jewish Community and the Wiesbaden Concentration Camp Committee took over the tasks of the Municipal Care Center. On December 8, 1945, it was transferred to the municipal welfare office under the management of Heinz Ranly and renamed the "Registration and Preliminary Examination Office for the Implementation of the Compensation Act" in 1949. It was now housed at Bahnhofstraße 61 and its files have been lost.

Rudolf Jesinghaus-Medicus took his own life in 1951.